Welcome! You have reached the Noonan lab data server. Here you can find the data associated with our publications. These data were moved here for security reasons. Apologies for any inconveniences.
Dutrow EV, Emera D, Yim K, Uebbing S, Kocher AA, Krenzer M, Nottoli T, Burkhardt DB, Krishnaswamy S, Louvi A, Noonan JP (2022): Modeling uniquely human gene regulatory function via targeted humanization of the mouse genome. Nature Communications 13:304.
Uebbing S, Gockley J, Reilly SK, Kocher AA, Geller E, Gandotra N, Scharfe C, Cotney J, Noonan JP (2021): Massively parallel discovery of human-specific substitutions that alter enhancer activity. PNAS 118:e2007049118.
Geller E, Gockley J, Emera D, Uebbing S, Cotney J, Noonan JP (2019): Massively parallel disruption of enhancers active during human corticogenesis. bioRxiv 852673.
Emera D, Yin J, Reilly SK, Gockley J, Noonan JP (2017): Origin and evolution of developmental enhancers in the mammalian neocortex. PNAS 113:E2617-E2626.
Cotney J, Muhle RA, Sanders SJ, Liu L, Willsey AJ, Niu W, Liu W, Klei L, Lei J, Yin J, Reilly SK, Tebbenkamp AT, Bichsel C, Pletikos M, Sestan N, Roeder K, State MW, Devlin B, Noonan JP (2015): The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopment. Nature Communications 6:6404.
Reilly SK, Yin J, Ayoub AE, Emera D, Leng J, Cotney J, Sarro R, Rakic P, Noonan JP (2015): Evolutionary changes in promoter and enhancer activity during human corticogenesis. Science 347:1155-1159.
Cotney J, Leng J, Yin J, Reilly SK, DeMare LE, Emera D, Ayoub AE, Rakic P, Noonan JP (2013): The evolution of lineage-specific regulatory activities in the human embryonic limb. Cell 154:185-196.
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